longobard#59
Ahogy mondod. Itt ez olvasható http://www.chemsoc.org/chembytes/ezine/1999/jourdier.htm
"Its use, however, has one major side effect - gastro-intestinal damage. Scruton's addition of CaCO3 buffered the aspirin and other buffering agents, such as MgO and MgCO3, have also been used in the hope that they might increase the absorption rate of aspirin and thereby reduce gastro-intestinal damage. Buffered aspirin is more rapidly absorbed from the gastro-intestinal tract, but by 1965 researchers generally accepted that this does not reduce incidences of indigestion. Scientists began developing a preparation of aspirin that prevents any contact with the stomach wall in the 1960s. The idea was to microencapsulate aspirin so that it would not dissolve in the stomach, yet would do so before being excreted. In 1970 chemists prepared such a formulation, which they named Colfarit. Each tablet contains 500mg aspirin in which every individual crystal is covered in a fine coating of ethyl cellulose. Aspirin is released gradually, with only tiny quantities in the stomach, the majority being released in the gut. Researchers established the safety of such enteric coated aspirin by endoscopic studies, although a recent report in The Lancet casts doubt on this safety."